The Evaluation of Hypoxia-Inducible Factor 1 in N-Nitro-L-Arginine Methyl Ester Preeclampsia Model of Pregnant Rats

Kaya A., Boztosun A., SECKIN H., GUVEN A. S., Kucukdurmaz Z., Gulturk S., ...Daha Fazla

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.59, sa.8, ss.1268-1272, 2011 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Sayı: 8
  • Basım Tarihi: 2011
  • Doi Numarası: 10.2310/jim.0b013e31822fff4a
  • Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1268-1272
  • Anahtar Kelimeler: hypoxia-inducible factor 1, preeclampsia, rat, SOLUBLE ENDOGLIN, OXIDE SYNTHESIS, BLOOD-PRESSURE, GROWTH-FACTOR, PLASMA-LEVELS, HYPERTENSION, EXPRESSION, PATHWAYS, BLOCKADE, SYNTHASE
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Objective: The objective of the study was to evaluate hypoxia-inducible factor 1 (HIF-1), which plays a major role in the stimulation of angiogenesis in placental tissues, by using immunohistochemical staining in preeclampsia model of rats, developed by N-nitro-L-arginine methyl ester (L-NAME)