Clinical Features and HSCT Outcome for SCID in Turkey

Ikinciogullari A., ÇAĞDAŞ AYVAZ D. N., Dogu F., Tugrul T., Karasu G., Haskologlu S., ...Daha Fazla

JOURNAL OF CLINICAL IMMUNOLOGY, cilt.39, sa.3, ss.316-323, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1007/s10875-019-00610-x
  • Dergi Adı: JOURNAL OF CLINICAL IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.316-323
  • Anahtar Kelimeler: Severe combined immune deficiency (SCID), Hematopoietic stem cell transplantation (HSCT), clinical features, outcome, STEM-CELL TRANSPLANTATION, SEVERE COMBINED IMMUNODEFICIENCY, IMMUNE RECONSTITUTION, SINGLE-CENTER, COHORT
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Severe combined immunodeficiency (SCID) is the most serious PID, characterized by T cell lymphopenia and lack of antigen-specific T cell and B cell immune responses, inevitably leading to death within the first year of life if hematopoietic stem cell transplantation (HSCT) is not performed.