The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions

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Demirkan N. C., Kesen Z., Akdag B., Larue L., Delmas V.

CLINICAL AND EXPERIMENTAL DERMATOLOGY, cilt.32, sa.6, ss.733-739, 2007 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 32 Sayı: 6
• Basım Tarihi: 2007
• Doi Numarası: 10.1111/j.1365-2230.2007.02507.x
• Dergi Adı: CLINICAL AND EXPERIMENTAL DERMATOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.733-739
• Akdeniz Üniversitesi Adresli: Hayır

Özet

Background. The tumour suppressor gene product, p16, is often inactivated during melanoma malignant progression. Although the importance of p16 in melanomas is well documented, its relationship with cyclin D1, beta-catenin and ultraviolet radiation (UVR) remains unclear.