Relation of Neutrophil-to-Lymphocyte Ratio With GRACE Risk Score to In-Hospital Cardiac Events in Patients With ST-Segment Elevated Myocardial Infarction

ONCEL R. C., Ucar M., Karakas M. S., AKDEMIR B., YANIKOGLU A., GULCAN A. R., ...More

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, vol.21, no.4, pp.383-388, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1177/1076029613505763
  • Journal Name: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.383-388
  • Keywords: GRACE risk score, inflammation, neutrophil-to-lymphocyte ratio, acute myocardial infarction, LONG-TERM MORTALITY, PERCUTANEOUS CORONARY INTERVENTION, NEUTROPHIL/LYMPHOCYTE RATIO, ANGIOGRAPHIC OUTCOMES, CARDIOVASCULAR RISK, PROGNOSTIC VALUE, PREDICTIVE-VALUE, ARTERY-DISEASE, HEART-FAILURE, ASSOCIATION
  • Akdeniz University Affiliated: Yes

Abstract

In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P < .001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P < .001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r = .803, P < .001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.