Relation of Neutrophil-to-Lymphocyte Ratio With GRACE Risk Score to In-Hospital Cardiac Events in Patients With ST-Segment Elevated Myocardial Infarction

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ONCEL R. C., Ucar M., Karakas M. S., AKDEMIR B., YANIKOGLU A., GULCAN A. R., ...Daha Fazla

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, cilt.21, sa.4, ss.383-388, 2015 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 21 Sayı: 4
• Basım Tarihi: 2015
• Doi Numarası: 10.1177/1076029613505763
• Dergi Adı: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.383-388
• Anahtar Kelimeler: GRACE risk score, inflammation, neutrophil-to-lymphocyte ratio, acute myocardial infarction, LONG-TERM MORTALITY, PERCUTANEOUS CORONARY INTERVENTION, NEUTROPHIL/LYMPHOCYTE RATIO, ANGIOGRAPHIC OUTCOMES, CARDIOVASCULAR RISK, PROGNOSTIC VALUE, PREDICTIVE-VALUE, ARTERY-DISEASE, HEART-FAILURE, ASSOCIATION
• Akdeniz Üniversitesi Adresli: Evet

Özet

In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P < .001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P < .001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r = .803, P < .001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.