Investigation of Torque Teno Virus (TTV) DNA as an immunological and virological marker in pediatric hematopoietic stem cell transplantation (HSCT) patients

Peker, Bilal; Daloglu, Aylin; GÖRZER, Irene; Puchhammer-Stockl, Elisabeth; Parkan, ÖMÜR; AKBAŞ, HİLÂL; Kintrup, GÜLEN; MUTLU, DERYA; KÜPESİZ, OSMAN; ÇOLAK, DİLEK

doi:10.1016/j.micpath.2020.104397

Investigation of Torque Teno Virus (TTV) DNA as an immunological and virological marker in pediatric hematopoietic stem cell transplantation (HSCT) patients

Peker B. O., Daloglu A. E., GÖRZER I., Puchhammer-Stockl E., Parkan O. M., AKBAŞ H., ...More

MICROBIAL PATHOGENESIS, vol.149, 2020 (SCI-Expanded)

Publication Type: Article / Article
Volume: 149
Publication Date: 2020
Doi Number: 10.1016/j.micpath.2020.104397
Journal Name: MICROBIAL PATHOGENESIS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
Keywords: Hematopoietic stem cell transplantation, Torque teno virus, Quantitative polymerase chain reaction, Biomarker, TORQUETENOVIRUS, IMMUNOSUPPRESSION, INFECTION, KINETICS, VIREMIA, CYTOMEGALOVIRUS, MAINTENANCE, ENGRAFTMENT, MANAGEMENT, DYNAMICS
Akdeniz University Affiliated: Yes

Abstract

Background: High viral loads are observed in Torque Teno Virus (TTV) infection after hematopoietic stem cell transplantation (HSCT). We aimed to analyze the kinetics of plasma TTV-DNA load in pediatric patients who received immunosuppressive therapy and developed infection complications in the first 100 days after HSCT.