Cardiac Transplant in a Child with Recurrent Thrombosis Due to Congenital Thrombophilic Mutations

Ozkan S., Atac F. B., Ozcobanoglu S., Uguz E., Sezgin A., Verdi H., ...More

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, vol.7, no.3, pp.188-191, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 3
  • Publication Date: 2009
  • Journal Name: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.188-191
  • Keywords: Factor V A4070G, Methylene tetrahydrofolate reductase C677T, Thrombosis, DEEP-VEIN THROMBOSIS, ACTIVATED PROTEIN-C, FACTOR-V, VENOUS THROMBOSIS, RISK FACTOR, HYPERHOMOCYSTEINEMIA, POLYMORPHISMS, PREVALENCE, SURGERY, DISEASE
  • Akdeniz University Affiliated: No

Abstract

A modified Blalock-Taussig shunt had been implanted 3 times to treat cyanosis to a patient who has uncorrectable congenital cardiac deformity. We repaired the entire pulmonary artery, from one hilus to the other, to prevent future stenosis while making cardiac transplant. Our patient was also heterozygous for 2 thrombophilic mutations: methylene tetrahydrofolate reductase C677T and Factor V A4070G. Congenital risk factors should be evaluated in patients who have experienced a thromboembolic event before cardiac surery.