PHENOLIC CONTENT AND BIOLOGICAL ACTIVITIES OF RHUS CORIARIA VAR. ZEBARIA

Mohammed F. S., AKGÜL H., SEVİNDİK M., KHALED B. M. T.

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.27, sa.8, ss.5694-5702, 2018 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 8
  • Basım Tarihi: 2018
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.5694-5702
  • Anahtar Kelimeler: Rhus coriaria var. zebaria, antioxidant, antimicrobial, DNA protective, cytotoxic effect, phenolic content, P-COUMARIC ACID, CHLOROGENIC ACID, BENZOIC-ACID, CAFFEIC ACID, ANTIMICROBIAL ACTIVITY, ANTIOXIDANT ACTIVITY, SYRINGIC ACID, SINAPIC ACID, IN-VITRO, HESPERIDIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The present study aimed to determine the biological activities and phenolic content in the endemic Rhus coriaria L. var. zebaria Shahbaz. plant collected in Duhok region in Iraq. Thus, plant antioxidant activity was determined with the DPPH method. Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) were measured with Rel Assay kits. DNA protective activity was determined using pBR 322 supercoiled DNA. The effects of the plant extracts were tested on A549 cell to determine the cytotoxic effects. Phenolic content was screened with the HPLC instrument. Antimicrobial activities were tested on 9 microorganisms using modified agar dilution method. The study findings demonstrated that R. coriaria var. zebaria had high level of biological activity. It was also determined that it contained Gallic acid, Catechin, Epicatechin, Syringic acid, Chlorogenic acid, Caffeic acid, Qumaric acid, Benzoic acid, t-phenolic, Hesperidin and Sinapic acid. The findings suggested that R. coriaria var. zebaria can be used as a natural source in pharmacology due to its high biological activities.