The analgesic efficacy of intraperitoneal local anaesthetic instillation after laparoscopic gynaecological procedures

Kayacan N., Arici G., Karsli B., Zorlu G., Erman M.

GYNAECOLOGICAL ENDOSCOPY, cilt.11, sa.6, ss.377-381, 2002 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 6
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1111/j.1365-2508.2002.00559.x
  • Dergi Adı: GYNAECOLOGICAL ENDOSCOPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.377-381
  • Anahtar Kelimeler: intraperitoneal bupivacaine, intraperitoneal ropivacaine, laparoscopy, postoperative analgesia, POSTOPERATIVE PAIN RELIEF, HERNIA REPAIR, DOUBLE-BLIND, BUPIVACAINE, CHOLECYSTECTOMY, ROPIVACAINE, PLACEBO, HYSTERECTOMY, INFILTRATION, TOXICITY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective Patients undergoing laparoscopic procedures may experience postoperative pain. We evaluated the effectiveness of intraperitoneal local anaesthetic instillation after laparoscopic gynaecological procedures.
Abstract

Objective Patients undergoing laparoscopic procedures may experience postoperative pain. We evaluated the effectiveness of intraperitoneal local anaesthetic instillation after laparoscopic gynaecological procedures. 

Design Randomized, double-blinded, placebo-controlled trial. 

Methods Patients were randomly assigned to one of three groups of 20 patients each. Those in group A received ropivacaine, 20 ml 0.75%, and those in group B received bupivacaine, 20 ml 0.5% intraperitoneally. Those in group C (the control group) received 20 ml 0.9% saline. Pain was assessed, using a visual analogue scale (VAS) and a verbal rating scale (VRS), at 30 min, 60 min, 2 h and 4 h after surgery. Total analgesic consumption and the time to first need for analgesia were also noted. 

Results VAS and VRS pain scores were significantly lower in the ropivacaine and bupivacaine groups compared with the placebo group. Patients in group A (ropivacaine) experienced less pain than those in group B (bupivacaine) for all measurements. The time to first need for analgesia was significantly later for the ropivacaine and bupivacaine groups compared with the placebo group. The total analgesic consumption was also significantly lower in those groups than in the placebo group. 

Conclusion The results indicated that both ropivacaine and bupivacaine were effective at preventing pain and the need for postoperative analgesic when intraperitoneally instilled. However, ropivacaine is the better choice because of its higher efficacy.