Correlates of benefit from neoadjuvant chemotherapy before radiotherapy in non-small cell lung cancer: a meta-analytical approach with meta-regression analysis


Bozcuk H., Artac M., Ozdogan M.

JOURNAL OF BUON, cilt.15, sa.1, ss.43-50, 2010 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 1
  • Basım Tarihi: 2010
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.43-50
  • Anahtar Kelimeler: chemotherapy, meta-analysis, meta-regression, neoadjuvant, non-small cell lung cancer, radiotherapy, RANDOMIZED CLINICAL-TRIALS, HIGH-DOSE RADIOTHERAPY, PHASE-III TRIAL, COMBINED CHEMORADIOTHERAPY, INDUCTION CHEMOTHERAPY, RADIATION-THERAPY, METAANALYSIS, QUALITY, CISPLATIN, PATTERNS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Induction chemotherapy before radiotherapy, although inferior to concomitant chemoradiotherapy, is still used in clinical practice, and improves survival compared to radiotherapy alone in unresectable non-small cell lung cancer (NSCLC). In this setting, we assessed the predictors of benefit from neoadjuvant chemotherapy before radiotherapy.