Correlates of benefit from neoadjuvant chemotherapy before radiotherapy in non-small cell lung cancer: a meta-analytical approach with meta-regression analysis


Bozcuk H., Artac M., Ozdogan M.

JOURNAL OF BUON, vol.15, no.1, pp.43-50, 2010 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 15 Issue: 1
  • Publication Date: 2010
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.43-50
  • Keywords: chemotherapy, meta-analysis, meta-regression, neoadjuvant, non-small cell lung cancer, radiotherapy, RANDOMIZED CLINICAL-TRIALS, HIGH-DOSE RADIOTHERAPY, PHASE-III TRIAL, COMBINED CHEMORADIOTHERAPY, INDUCTION CHEMOTHERAPY, RADIATION-THERAPY, METAANALYSIS, QUALITY, CISPLATIN, PATTERNS
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Induction chemotherapy before radiotherapy, although inferior to concomitant chemoradiotherapy, is still used in clinical practice, and improves survival compared to radiotherapy alone in unresectable non-small cell lung cancer (NSCLC). In this setting, we assessed the predictors of benefit from neoadjuvant chemotherapy before radiotherapy.