Central diabetes insipitus in a patient with congenital toxoplasmosis

Oygur N., YILMAZ G., OZKAYNAK C., GUR GUVEN A.

AMERICAN JOURNAL OF PERINATOLOGY, vol.15, no.3, pp.191-192, 1998 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 1998
  • Doi Number: 10.1055/s-2007-993924
  • Journal Name: AMERICAN JOURNAL OF PERINATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.191-192
  • Keywords: congenital toxoplasmosis, diabetes insipitus
  • Akdeniz University Affiliated: Yes

Abstract

A 33-day-old male infant who developed central diabetes insipitus as a complication of congenital toxoplasmosis is presented. He had polyuria and hypernatremia on admission and responded to Intranasal desmopressin acetate with the normalization of abovementioned findings. Computed tomographic (CT) scan of the brain showed obstructive hydrocephaly with periventricular and right basal ganglion calcification. CT scan of the pituitary gland, thyroid function tests, and serum cortisol levels were all normal. This is the first report of isolated diabetes insipitus with congenital toxoplasmosis in literature and central diabetes insipitus should be remembered if polyuria and hypernatremia develops in a patient with congenital toxoplasmosis.