Simvastatin therapy in lymphocyte cross-match-positive kidney transplantation candidates

Yakupoglu, U; Kocak, HÜSEYİN; Karatas, GU; Yakupoglu, Y; Dinckan, A; Kececioglu, N; Gurkan, A; Demirbas, A; Yegin, O; Tuncer, M

doi:10.1016/j.transproceed.2005.07.034

Simvastatin therapy in lymphocyte cross-match-positive kidney transplantation candidates

Yakupoglu U., Kocak H., Karatas G., Yakupoglu Y., Dinckan A., Kececioglu N., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.37, sa.7, ss.2933-2935, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 37 Sayı: 7
Basım Tarihi: 2005
Doi Numarası: 10.1016/j.transproceed.2005.07.034
Dergi Adı: TRANSPLANTATION PROCEEDINGS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2933-2935
Akdeniz Üniversitesi Adresli: Evet

Özet

Objectives. Recent identification of several mechanisms by which statins decrease recruitment of monocytes and T cells into the arterial wall and inhibit both T-cell and B-cell activation and proliferation in vitro prompted us to study the immunomodulatory effects of statins. In this study, we examined the effect of simvastatin therapy on lymphocyte cross-match positivity in kidney transplantation candidates.