The effects of iloprost and vitamin C on kidney as a remote organ after ischemia/reperfusion of lower extremities

Ozcan A. V., Sacar M., Aybek H., Bir F., Demir S., Onem G., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.140, sa.1, ss.20-26, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 140 Sayı: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jss.2006.04.031
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.20-26
  • Anahtar Kelimeler: ischemia/reperfusion, remote organ damage, kidney injury, iloprost, vitamin C, ISCHEMIA-REPERFUSION INJURY, ACUTE LUNG INJURY, SKELETAL-MUSCLE, ASCORBIC-ACID, HEPATIC ISCHEMIA/REPERFUSION, TISSUE-DAMAGE, CELL-ADHESION, NITRIC-OXIDE, SPINAL-CORD, PROSTACYCLIN
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background. Abdominal aortic surgery can cause ischemic/reperfusion (I/R) injury in not only the lower extremities, but also in the remote organs and tissues such as lungs, kidneys, heart, and liver during abdominal aortic surgery. It can result in mortality and morbidity because of the remote organ injury in early postoperative period. In this study, we investigate the effects of iloprost and vitamin C on the kidney remote organ damage after I/R following abdominal aortic surgery.