Chemical peritonitis associated with high dialysate acetaldehyde concentrations

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Tuncer H., Sarikaya M., Sezer T., Ozcan S., SÜLEYMANLAR G., Yakupoglu G., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.15, sa.12, ss.2037-2040, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 12
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1093/ndt/15.12.2037
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2037-2040
  • Anahtar Kelimeler: acetaldehyde, chemical peritonitis, dark dialysate, glucose degradation products, peritoneal dialysis, GLUCOSE DEGRADATION PRODUCTS, MESOTHELIAL CELLS, IN-VITRO, FLUIDS, INVITRO
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background. During the standard heat sterilization process of lactate-buffered peritoneal dialysis (PD) solutions, glucose degrades to form compounds called glucose degradation products such as acetaldehyde, formaldehyde, or glyoxal. Despite evidence that these products may be responsible for some in vitro cytotoxic effects induced by commercially available PD fluids, data on their acute or chronic effects on the human peritoneum is scarce.