Noninvasive MRI Measurement of the Absolute Cerebral Blood Volume-Cerebral Blood Flow Relationship During Visual Stimulation in Healthy Humans
MAGNETIC RESONANCE IN MEDICINE, vol.72, no.3, pp.864-875, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 72 Issue: 3
- Publication Date: 2014
- Doi Number: 10.1002/mrm.24984
- Journal Name: MAGNETIC RESONANCE IN MEDICINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.864-875
- Keywords: cerebral blood volume, cerebral blood flow, brain activation, blood oxygenation level-dependent, functional MRI, Grubb's relationship, visual stimulation, POSITRON-EMISSION-TOMOGRAPHY, VASCULAR-SPACE-OCCUPANCY, OXYGEN EXTRACTION FRACTION, RODENT BARREL CORTEX, SPIN-LABELING MRI, FUNCTIONAL MRI, BOLD FMRI, OXIDATIVE-METABOLISM, NEURAL ACTIVITY, HUMAN BRAIN
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: Yes
Abstract
Purpose: The relationship between cerebral blood volume (CBV) and cerebral blood flow (CBF) underlies blood oxygenation level-dependent functional MRI signal. This study investigates the potential for improved characterization of the CBV-CBF relationship in humans, and examines sex effects as well as spatial variations in the CBV-CBF relationship.