Noninvasive MRI Measurement of the Absolute Cerebral Blood Volume-Cerebral Blood Flow Relationship During Visual Stimulation in Healthy Humans

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Ciris P., Qiu M., Constable R. T.

MAGNETIC RESONANCE IN MEDICINE, cilt.72, sa.3, ss.864-875, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1002/mrm.24984
  • Dergi Adı: MAGNETIC RESONANCE IN MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.864-875
  • Anahtar Kelimeler: cerebral blood volume, cerebral blood flow, brain activation, blood oxygenation level-dependent, functional MRI, Grubb's relationship, visual stimulation, POSITRON-EMISSION-TOMOGRAPHY, VASCULAR-SPACE-OCCUPANCY, OXYGEN EXTRACTION FRACTION, RODENT BARREL CORTEX, SPIN-LABELING MRI, FUNCTIONAL MRI, BOLD FMRI, OXIDATIVE-METABOLISM, NEURAL ACTIVITY, HUMAN BRAIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: The relationship between cerebral blood volume (CBV) and cerebral blood flow (CBF) underlies blood oxygenation level-dependent functional MRI signal. This study investigates the potential for improved characterization of the CBV-CBF relationship in humans, and examines sex effects as well as spatial variations in the CBV-CBF relationship.