Multiple Sclerosis and Related Disorders, cilt.109, 2026 (SCI-Expanded, Scopus)
Background: Women with Multiple Sclerosis (MS) face significant challenges in their sexual life, including physical limitations and emotional barriers. The PLISSIT model offers a structured framework for counselors to address these issues effectively. This study aimed to investigate the effects of counseling interventions based on the PLISSIT model on the sexual life of women with MS through randomized controlled trials. Methods: This was a systematic review and meta-analysis study. Databases such as Google Scholar, OpenAIRE, Web of Science, Social Sciences Citation Index, Academic Search Ultimate, Complementary Index, Scopus, CINAHL Complete, MEDLINE, and PubMed were searched for English-language studies without year restrictions up to February 2024. The PRISMA guidelines were followed. Comprehensive Meta-Analysis 3 software was used for data analysis. Two researchers independently assessed the quality of the included studies using the Cochrane Collaboration tool. Results: Three randomized controlled trials with a total of 232 participants were included in this study. Counseling based on the PLISSIT model was found to have a high and positive effect on the sexual life of women with MS (Hedges' g = 0.927, 95 % CI = -1.122 to 2.976, p = 0.375). Conclusions: This meta-analysis suggests that sexual counseling based on the PLISSIT model may have a positive impact on the sexual life of women with MS, although statistically significant results were not obtained. Future research with larger sample sizes and more homogeneous study groups may provide clearer results.