The role of High Mobility Group Box 1 (HMGB1) in colorectal cancer
MEDICAL SCIENCE MONITOR, cilt.20, ss.530-537, 2014 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20
- Basım Tarihi: 2014
- Doi Numarası: 10.12659/msm.890531
- Dergi Adı: MEDICAL SCIENCE MONITOR
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.530-537
- Anahtar Kelimeler: Colorectal Neoplasms - pathology, HMGB1 Protein - diagnostic use, Prognosis, SQUAMOUS-CELL CARCINOMA, COLON-CANCER, CYCLOOXYGENASE-2 EXPRESSION, CLINICAL-SIGNIFICANCE, IN-VITRO, PROGRESSION, PROTEINS, PROGNOSIS, OVEREXPRESSION, APOPTOSIS
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Akdeniz Üniversitesi Adresli: Evet
Özet
Background: HMGB1, the most important member of the high mobility group box protein family, is a nuclear protein with different functions in the cell; it has a role in cancer progression, angiogenesis, invasion, and metastasis development. We studied the expression of HMGB1 and whether it is a prognostic factor in colorectal carcinoma.