Carotid artery intima-media thickness correlates with oxidative stress in chronic haemodialysis patients with accelerated atherosclerosis
NEPHROLOGY DIALYSIS TRANSPLANTATION, vol.23, no.5, pp.1697-1703, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 23 Issue: 5
- Publication Date: 2008
- Doi Number: 10.1093/ndt/gfm906
- Journal Name: NEPHROLOGY DIALYSIS TRANSPLANTATION
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1697-1703
- Keywords: carotid artery intima media thickness, chronic haemodialysis patients, oxidative stress, CHRONIC-RENAL-FAILURE, CARDIOVASCULAR RISK-FACTORS, ACETATE-FREE BIOFILTRATION, NITRIC-OXIDE PRODUCTION, MYOCARDIAL-INFARCTION, DIALYSIS HYPOTENSION, DIABETES-MELLITUS, WALL THICKNESS, TNF-ALPHA, DISEASE
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: Yes
Abstract
Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). Increased oxidative stress might be the major factor leading to high cardiovascular mortality rate in HD patients. The aim of our study was to clarify effects of uraemia and dialysis on oxidative stress parameters and explore the relation between oxidative stress markers and carotid artery intima-media thickness (CIMT) as an indicator of atherosclerosis.