Uterine giant cell carcinoma: a case report and review of the literature

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Aydin H. A., TUNCER H. A., ERDOĞAN G., ŞİMŞEK T.

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.16, sa.1, ss.76-79, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/tjod.galenos.2018.31855
  • Dergi Adı: TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.76-79
  • Anahtar Kelimeler: Endometrial carcinoma, giant cell tumor, uterus, ENDOMETRIUM
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Endometrial carcinoma is the most common genital malignancy in women. Endometrioid type is the most common variant of endometrial carcinoma described in literature. Giant cell carcinoma is a rare, and infrequently reported variant of endometrial carcinoma. We present a 75-year-old patient admitted with vaginal bleeding. Transvaginal ultrasound revealed a 26x28 mm hypodense lesion without any adnexal pathology. The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and bilateral pelvic, and paraaortic lymph node dissection. The final histopathology report indicated a 3.8x2x9 cm giant cell carcinoma variant of endometrial carcinoma and one positive external iliac lymph node metastasis. Administration of adjuvant carboplatin and paclitaxel chemotherapy was given. As far as we know, this is the fifteenth case reported in the English literature.