Cerebellar hemangioblastoma associated with diffuse neonatal hemangiomatosis in an infant

Patiroglu T., Sarici D., ÜNAL E., Yikilmaz A., Tucer B., KARAKÜKCÜ M., ...More

CHILDS NERVOUS SYSTEM, vol.28, no.10, pp.1801-1805, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 10
  • Publication Date: 2012
  • Doi Number: 10.1007/s00381-012-1858-x
  • Journal Name: CHILDS NERVOUS SYSTEM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1801-1805
  • Keywords: Cerebellum, Hemangioblastoma, Diffuse neonatal hemangiomatosis, Newborn, CENTRAL-NERVOUS-SYSTEM, VONHIPPEL-LINDAU DISEASE, OF-THE-LITERATURE, SURGICAL-MANAGEMENT
  • Akdeniz University Affiliated: Yes

Abstract

Hemangioblastomas (HBLs) comprise approximately 2 % of all primary central nervous system (CNS) tumors. Although histological features of this rare tumor are generally benign, its outcome is often unfavorable due to high risk of recurrence and multifocal localization. HBLs can be detected as sporadic or associated with Von Hippel-Lindau disease. Diffuse neonatal hemangiomatosis (DNH) presents with multiple, progressive, rapidly growing cutaneous hemangiomas associated with widespread visceral hemangiomas in the liver, lungs, gastrointestinal tract, brain, and meninges. DNH with predominant CNS involvement is rarely reported. Herein, we present a neonatal case of cerebellar HBL associated with DNH.