The Necessity of Cytoreductive Nephrectomy in Patients With Metastatic Renal Cell Carcinoma Using Antiangiogenic Targeted Therapy After Interferon Alfa-2b

Mutlu H., Gunduz S., Buyukcelik A., Yildiz O., Uysal M., Tural D., ...More

CLINICAL GENITOURINARY CANCER, vol.12, no.6, pp.447-450, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1016/j.clgc.2014.06.006
  • Journal Name: CLINICAL GENITOURINARY CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.447-450
  • Keywords: Angiogenesis, Nephrectomy, Prognosis, Renal cell cancer, Survival, ERA, SURVIVAL, CANCER, IMPACT, ALPHA
  • Akdeniz University Affiliated: Yes

Abstract

The effects of cytoreductive nephrectomy (CRN) on prognosis of patients with metastatic renal cell cancer (RCC) using antiangiogenic targeted agents were evaluated. The median overall survival was significantly higher in the group that received CRN (P = .034). We speculate that CRN is still an important part of treatment modalities in patients with metastatic RCC in modern era targeted therapy, which is currently the best systemic therapy.