Evaluation of Aspergillus Lateral-Flow Test in Serum Samples of Pediatric Patients

FELEK R., Erman-Daloglu A., ÖZHAK B., Ogunc D., ÖNGÜT G., Gunseren F., ...Daha Fazla

CLINICAL LABORATORY, cilt.67, sa.4, ss.974-980, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.7754/clin.lab.2020.200746
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.974-980
  • Anahtar Kelimeler: invasive aspergillosis, Aspergillus lateral flow device test, hematologic malignancy, BETA-D-GLUCAN, INVASIVE ASPERGILLOSIS, DIAGNOSIS, GALACTOMANNAN, DEVICE, PERFORMANCE, ASSAY, PCR
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Diagnosis of invasive aspergillosis (IA) in patients with hematologic malignancies and under the risk of IA may be uncertain or may delay because of nonspecific clinical presentation of the patients and difficult application techniques of conventional methods. Early diagnosis can provide initial antifungal therapy and prevent high mortality. In this study, we investigated the performance of an Aspergillus lateral-flow device (LFD) test (OLM Diagnostics, Newcastle upon Tyne, United Kingdom) for the diagnosis of IA in pediatric febrile neutropenic patients with hematologic malignancies.