Effects of statin use on total oxidant and antoxidant capacity and ceruloplasmin activity
CLINICAL AND INVESTIGATIVE MEDICINE, vol.33, no.5, 2010 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 33 Issue: 5
- Publication Date: 2010
- Journal Name: CLINICAL AND INVESTIGATIVE MEDICINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Akdeniz University Affiliated: No
Abstract
Purpose: Oxidative damage plays an important role in atherosclerosis development. Statin drugs have anti-oxidant properties, but the clinical value of their antioxidant properties remains unclear. In this study, our aims were: (1) to assess the anti-oxidant effects of statins in patients with coronary artery disease (CAD) using a newly developed valid measure of total oxidant and anti-oxidant capacity; and (2) to identify whether statins influence ceruloplamin levels.