Effects of statin use on total oxidant and antoxidant capacity and ceruloplasmin activity
CLINICAL AND INVESTIGATIVE MEDICINE, cilt.33, sa.5, 2010 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 5
- Basım Tarihi: 2010
- Dergi Adı: CLINICAL AND INVESTIGATIVE MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Akdeniz Üniversitesi Adresli: Hayır
Özet
Purpose: Oxidative damage plays an important role in atherosclerosis development. Statin drugs have anti-oxidant properties, but the clinical value of their antioxidant properties remains unclear. In this study, our aims were: (1) to assess the anti-oxidant effects of statins in patients with coronary artery disease (CAD) using a newly developed valid measure of total oxidant and anti-oxidant capacity; and (2) to identify whether statins influence ceruloplamin levels.