Akademik Veri Yönetim Sistemi
Annals of Surgery Open, cilt.5, 2024 (Hakemli Dergi)
Analyze our long-term experience with a less-popularized but stalwart approach, the stapled end-to-side ileocolic anastomosis.
The choice of technical approach to ileocolic anastomosis after ileocecal resection for Crohn’s disease affects surgical outcomes and recurrence. Yet, despite heterogeneous data from different anastomotic configurations, there remains no clear guidance as to the optimal technique.
In a retrospective cohort design, patients undergoing ileocolic anastomosis in the setting of Crohn’s disease between 2016 and 2021 at two institutions were identified. Patient characteristics and surgical outcomes in terms of recurrence (surgical, clinical, and endoscopic) were studied.
In total, 211 patients were included. Before surgery, 80% were exposed to at least 1 cycle of systemic steroids and 71% had at least 1 biologic agent; 60% exhibited penetrating disease and 38% developed an intra-abdominal abscess. After surgery, one anastomosis leaked (0.5%). Over 2.4 years of follow-up (IQR = 1.3–3.9), surgical recurrence was 0.9%. Two-year overall recurrence-free and endoscopic recurrence-free survivals were 74% and 85% (95% CI = 68–81 and 80–91), respectively. The adjusted hazard ratio of endoscopic recurrence was 3.0 (95% CI = 1.4–6.2) for males and 5.2 (1.2–22) for patients who received systemic steroids before the surgery.
The stapled end-to-side anastomosis is an efficient, reliable, and reproducible approach to maintain bowel continuity after ileocecal resection with durable outcomes. Our outcomes demonstrate low rates of disease recurrence and stand favorably in comparison to other more technically complex or protracted anastomotic approaches. This anastomosis is an ideal reconstructive approach after ileocecal resection for Crohn’s disease.