Evaluation of MALDI-TOF-MS for the Identification of Yeast Isolates Causing Bloodstream Infection
CLINICAL LABORATORY, cilt.63, sa.4, ss.699-703, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 63 Sayı: 4
- Basım Tarihi: 2017
- Doi Numarası: 10.7754/clin.lab.2016.161101
- Dergi Adı: CLINICAL LABORATORY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.699-703
- Anahtar Kelimeler: MALDI-TOF MS, identification of yeasts, bloodstream infection, FLIGHT MASS-SPECTROMETRY, DESORPTION IONIZATION-TIME, MICROBIOLOGY LABORATORIES, RAPID IDENTIFICATION
- Akdeniz Üniversitesi Adresli: Evet
Özet
Background: Infections due to Candida species are major causes of morbidity and mortality in humans, causing a diverse spectrum of clinical disease ranging from superficial and mucosal infections to invasive disease. Several authors have demonstrated that mortality is closely linked to both timing of therapy and/or source control. The rapid identification of pathogenic species is helpful to start timely and effective antifungal therapy. The aim of this study was to assess the performance of the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) system for the correct and rapid identification of yeast isolates causing bloodstream infection.