Evaluation of MALDI-TOF-MS for the Identification of Yeast Isolates Causing Bloodstream Infection

TURHAN Ö., Ozhak-Baysan B., HERNANDEZ O. Z., er H., SARITAS Z. E., ÖNGÜT G., ...Daha Fazla

CLINICAL LABORATORY, cilt.63, sa.4, ss.699-703, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.7754/clin.lab.2016.161101
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.699-703
  • Anahtar Kelimeler: MALDI-TOF MS, identification of yeasts, bloodstream infection, FLIGHT MASS-SPECTROMETRY, DESORPTION IONIZATION-TIME, MICROBIOLOGY LABORATORIES, RAPID IDENTIFICATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Infections due to Candida species are major causes of morbidity and mortality in humans, causing a diverse spectrum of clinical disease ranging from superficial and mucosal infections to invasive disease. Several authors have demonstrated that mortality is closely linked to both timing of therapy and/or source control. The rapid identification of pathogenic species is helpful to start timely and effective antifungal therapy. The aim of this study was to assess the performance of the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) system for the correct and rapid identification of yeast isolates causing bloodstream infection.