Seasonal Association of Immune Thrombocytopenia in Adults

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Tombak A., Boztepe B., Tiftik N., Comert M., SALİM O., Aydin K., ...More

BALKAN MEDICAL JOURNAL, vol.32, no.4, pp.347-351, 2015 (SCI-Expanded, Scopus, TRDizin)

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.5152/balkanmedj.2015.151223
  • Journal Name: BALKAN MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.347-351
  • Keywords: Allergens, immune thrombocytopenia, pollen, seasons, REGULATORY T-CELLS, PURPURA, EPIDEMIOLOGY, MANAGEMENT, VACCINES, DATABASE, RISK
  • Open Archive Collection: AVESIS Open Access Collection
  • Akdeniz University Affiliated: Yes

Abstract

Background: Immune thrombocytopenia (ITP) is an autoimmune disorder. It is characterized by thrombocytopenia due to thrombocyte destruction mediated by auto-antibodies; however, cytotoxic and defective regulatory T-lymphocytes play an important role in its pathogenesis. While childhood ITP is usually acute, self-limiting and generally seasonal in nature, ITP in adults is usually chronic; its relation with seasons has not been studied.