Akademik Veri Yönetim Sistemi
Radiation Physics and Chemistry, cilt.225, 2024 (SCI-Expanded)
Purpose: The study aims to investigate the effect of sodium arsenite (NaAsO2) on radiation permeability in biological tissues of rats, challenging existing literature claims about NaAsO2's influence on the density of bones. The motivation is determining whether exposure alters radiation permeability within a defined range of radiological energy. Should any changes be observed, radiation protection guidelines may necessitate the use of lower energy levels in imaging procedures involving such exposure. This consideration is vital for ensuring adherence to radiation safety standards, particularly in medical imaging, where minimizing patient and operator exposure to radiation is paramount. Materials and methods: In this study, rats were divided into two groups: a control group and a NaAsO2-treated group. After the treatment period, these animals were euthanized to collect their femurs and tibias for further analysis. The elemental composition of these bones was then meticulously examined using Scanning Electron Microscopy (SEM), enhanced by Energy-dispersive X-ray Spectrometry (EDX). Monte Carlo Simulation codes of MCNP6 and PHITS 3.22 were used for investigate photon induced interactions. These powerful tools allowed us to assess the gamma-ray attenuation properties of the collected samples. For an accurate comparison and analysis, we referred to the NIST database using the WinXCom program. Furthermore, the study explored the effects of charged particles on the bone samples, employing the SRIM code for this purpose. This part of the research was crucial to understanding the interactions at a more detailed level. We calculated the photon attenuation parameters for radiological energies up to 0.5 MeV and also investigated the interactions of charged particles with energies as high as 15 MeV. Results: In groups treated with NaAsO2, while there is less reduction in mass attenuation coefficients, larger differences have been observed in linear attenuation coefficients. Notably, a decrease in the linear attenuation coefficient has been observed in the NaAs Tibia group. Conclusion: The application of sodium arsenite (NaAsO2) results in a reduction in the Linear Attenuation Coefficient, necessitating a detailed investigation to determine whether this decrease also affects the Hounsfield unit, in accordance with the ALARA (As Low As Reasonably Achievable) principle that guides radiation safety protocols.