The Expression of MMP-11 In Benign Meningiomas

Ayan E., BOZKURT S., CERCI A., Altas M., Bolukbasi F., ELMACI I., ...More

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.31, no.1, pp.164-174, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2014
  • Journal Name: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.164-174
  • Keywords: Meningioma, MMP11, Extracellular Matrix, STROMELYSIN-3, CLASSIFICATION, CANCER, TUMORS, CELLS
  • Akdeniz University Affiliated: Yes

Abstract

The WHO categorises tumours based on their histological properties; however, this classification falls short of understanding their biological behaviours. Recently, there has been an increase in the number of studies on extracellular matrix components with the aim of understanding the biological behaviours of tumours. MMP-11 is a metalloproteinase from the MMP family that has a different expression pattern, mechanism of action, and substrate range compared with the other members of this family.