Associations between cytokine gene polymorphisms and rheumatoid arthritis in Turkish population

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YÜCEL B., Sumer C., Gok I., KARKUCAK M., Alemdaroglu E., UÇAR F.

NORTHERN CLINICS OF ISTANBUL, vol.7, no.6, pp.563-571, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.14744/nci.2020.70845
  • Journal Name: NORTHERN CLINICS OF ISTANBUL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.563-571
  • Keywords: Cytokine polymorphism, PCR-SSP, rheumatoid arthritis, INTERLEUKIN-1, PATHOGENESIS, IL-1
  • Open Archive Collection: AVESIS Open Access Collection
  • Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: Various cytokine polymorphisms have been associated with genetic risk factors predisposing to Rheumatoid Arthritis (RA) in different populations. To predict the clinical outcome as well as response to therapy in RA, studies aimed to describe genetic markers. The present study aims to search for polymorphisms of 13 cytokine coding genes in the Eastern Black Sea Region of Turkey.