Associations between cytokine gene polymorphisms and rheumatoid arthritis in Turkish population

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YÜCEL B., Sumer C., Gok I., KARKUCAK M., Alemdaroglu E., UÇAR F.

NORTHERN CLINICS OF ISTANBUL, cilt.7, sa.6, ss.563-571, 2020 (ESCI, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.14744/nci.2020.70845
  • Dergi Adı: NORTHERN CLINICS OF ISTANBUL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.563-571
  • Anahtar Kelimeler: Cytokine polymorphism, PCR-SSP, rheumatoid arthritis, INTERLEUKIN-1, PATHOGENESIS, IL-1
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Various cytokine polymorphisms have been associated with genetic risk factors predisposing to Rheumatoid Arthritis (RA) in different populations. To predict the clinical outcome as well as response to therapy in RA, studies aimed to describe genetic markers. The present study aims to search for polymorphisms of 13 cytokine coding genes in the Eastern Black Sea Region of Turkey.