MEFV gene variation R202Q is associated with metabolic syndrome

Balkarli A., Akyol M., Tepeli E., Elmas L., Cobankara V.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.20, sa.15, ss.3255-3261, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 15
  • Basım Tarihi: 2016
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3255-3261
  • Anahtar Kelimeler: Metabolic syndrome, Familial Mediterranean Fever, MEFV gene variation, Association, FAMILIAL MEDITERRANEAN FEVER, INSULIN-RESISTANCE, OBESITY, POLYMORPHISMS, PATHOGENESIS, EXPRESSION, DISEASES, RECEPTOR, GLUCOSE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: MEFV (Mediterranean fever) gene encoding pyrin regulates inflammatory responses. It has been shown that MEFV gene variations are associated with higher acute phase responses and altered course in the different inflammatory diseases. MEFV gene variations may affect the course of metabolic syndrome components.