MEFV gene variation R202Q is associated with metabolic syndrome

Balkarli, A.; Akyol, M.; Tepeli, E.; Elmas, L.; Cobankara, V.

MEFV gene variation R202Q is associated with metabolic syndrome

Balkarli A., Akyol M., Tepeli E., Elmas L., Cobankara V.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.20, no.15, pp.3255-3261, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 20 Issue: 15
Publication Date: 2016
Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.3255-3261
Keywords: Metabolic syndrome, Familial Mediterranean Fever, MEFV gene variation, Association, FAMILIAL MEDITERRANEAN FEVER, INSULIN-RESISTANCE, OBESITY, POLYMORPHISMS, PATHOGENESIS, EXPRESSION, DISEASES, RECEPTOR, GLUCOSE
Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: MEFV (Mediterranean fever) gene encoding pyrin regulates inflammatory responses. It has been shown that MEFV gene variations are associated with higher acute phase responses and altered course in the different inflammatory diseases. MEFV gene variations may affect the course of metabolic syndrome components.