MEFV gene variation R202Q is associated with metabolic syndrome

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Balkarli A., Akyol M., Tepeli E., Elmas L., Cobankara V.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.20, no.15, pp.3255-3261, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 20 Issue: 15
• Publication Date: 2016
• Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.3255-3261
• Keywords: Metabolic syndrome, Familial Mediterranean Fever, MEFV gene variation, Association, FAMILIAL MEDITERRANEAN FEVER, INSULIN-RESISTANCE, OBESITY, POLYMORPHISMS, PATHOGENESIS, EXPRESSION, DISEASES, RECEPTOR, GLUCOSE
• Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: MEFV (Mediterranean fever) gene encoding pyrin regulates inflammatory responses. It has been shown that MEFV gene variations are associated with higher acute phase responses and altered course in the different inflammatory diseases. MEFV gene variations may affect the course of metabolic syndrome components.