Mitochondrial ATPase Subunit 6 and Cytochrome B Gene Variations in Obese Turkish Children

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DEMIR D., TURKKAHRAMAN D., SAMUR A. A., LULECI G., Akcurin S., Alper O. M.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.6, sa.4, ss.209-215, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/jcrpe.1601
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.209-215
  • Anahtar Kelimeler: Mitochondrial ATPase-6, mitochondrial cytochrome b, obesity, single nucleotide polymorphism, CHILDHOOD OBESITY, RISK-FACTORS, DNA, POLYMORPHISM, SEQUENCE, PREVALENCE, LONGEVITY, TURKEY, GENOME, BIAS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Due to the importance of energy metabolism in mitochondria, mitochondrial genome variations are evaluated in energy-related diseases such as obesity. To date, several nuclear genes were found to be related to obesity. Our aim in this study was to investigate the presence of polymorphisms in mitochondrial ATPase subunit 6 (mt-ATP6) and cytochrome b (mt-CytB) genes that may be associated with childhood obesity.