Unfolded protein response prevents blastocyst formation during preimplantation embryo development in vitro

Basar M., Bozkurt I., Guzeloglu-Kayisli O., Sozen B., Tekmen I., Schatz F., ...Daha Fazla

FERTILITY AND STERILITY, cilt.102, sa.6, ss.1777-1784, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 102 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.fertnstert.2014.09.004
  • Dergi Adı: FERTILITY AND STERILITY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1777-1784
  • Anahtar Kelimeler: Preimplantation embryo development, endoplasmic reticulum stress, unfolded protein response, apoptosis, developmental arrest, ENDOPLASMIC-RETICULUM STRESS, ER STRESS, MITOCHONDRIAL PATHWAY, CELL-DEATH, APOPTOSIS, XBP-1, CHOP, ACTIVATION, INDUCTION, CASPASE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: To study the effect of increased endoplasmic reticulum (ER) stress as a major nongenomic mechanism for arrested blastocyst development.