Trends and factors associated with modification or discontinuation of the initial antiretroviral regimen during the first year of treatment in the Turkish HIV-TR Cohort, 2011-2017


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KORTEN V., Gokengin D., Eren G., Yildirmak T., Gencer S., Eraksoy H., ...More

AIDS RESEARCH AND THERAPY, vol.18, no.1, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1186/s12981-020-00328-6
  • Journal Name: AIDS RESEARCH AND THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Keywords: Antiretroviral therapy, Treatment modification, Integrase strand transfer inhibitor, Treatment outcome, Cohort study
  • Akdeniz University Affiliated: Yes

Abstract

Background: There is limited evidence on the modification or stopping of antiretroviral therapy (ART) regimens, including novel antiretroviral drugs. The aim of this study was to evaluate the discontinuation of first ART before and after the availability of better tolerated and less complex regimens by comparing the frequency, reasons and associations with patient characteristics.