An evaluation of vardenafil as a calcium channel blocker in pulmonary artery in rats

Minareci E., Sadan G.

INDIAN JOURNAL OF PHARMACOLOGY, cilt.46, sa.2, ss.185-190, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4103/0253-7613.129315
  • Dergi Adı: INDIAN JOURNAL OF PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.185-190
  • Anahtar Kelimeler: Calcium, phosphodiesterase type 5 inhibitors, pulmonary artery, vardenafil, SMOOTH-MUSCLE, VASCULAR-TONE, INHIBITORS SILDENAFIL, HYPERTENSION, TADALAFIL, ENDOTHELIUM, MECHANISMS, THERAPY, AORTA
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Vardenafil was reported to relax rat pulmonary artery through endothelium-dependent mechanisms. The aim of this in vitro study was to investigate other related mechanisms for this effect.