The Cutoff Level for Urine Protein in Urine Immunofixation Electrophoresis

Ellidag H. Y., Curek G., Eren E., Aydin O., Yilmaz N.

CLINICAL LABORATORY, cilt.61, sa.10, ss.1525-1530, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.7754/clin.lab.2015.150230
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1525-1530
  • Anahtar Kelimeler: electrophoresis, monoclonal gammopathy, multiple myeloma, Bence Jones proteinuria, urine protein, urine albumin, MONOCLONAL LIGHT-CHAINS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Immunofixation electrophoresis (IFE) maintains its importance in diagnosing monoclonal gammopathies. In particular, urine IFE detects free light chains (FLC) in urine samples even at low concentrations and offers higher sensitivity compared to serum electrophoresis and serum IFE. The aim of the present study was to determine the place and significance of quantitative urinary protein measurement before IFE in interpreting the results of subsequent IFE and to determine the most appropriate protein concentrations for the appearance of bands.