Increased urotensin-II activity in patients with Raynaud's phenomenon and systemic lupus erythematosus
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, vol.14, no.3, pp.276-281, 2011 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 14 Issue: 3
- Publication Date: 2011
- Doi Number: 10.1111/j.1756-185x.2011.01597.x
- Journal Name: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.276-281
- Keywords: Raynaud's phenomenon, systemic lupus erythematosus, urotensin-II, ENDOTHELIAL DYSFUNCTION, PULMONARY-HYPERTENSION, DISEASE-ACTIVITY, RECEPTOR GPR14, PLASMA-LEVELS, NITRIC-OXIDE, ATHEROSCLEROSIS, LOCALIZATION, RESPONSES, HEALTH
- Akdeniz University Affiliated: No
Abstract
Aim: Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear.