Increased urotensin-II activity in patients with Raynaud's phenomenon and systemic lupus erythematosus

Buyukhatipoglu H., BUYUKASLAN H., Pehlivan Y., Ceylan N., Ulas T., Tarakcioglu M., ...Daha Fazla

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, cilt.14, sa.3, ss.276-281, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1111/j.1756-185x.2011.01597.x
  • Dergi Adı: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.276-281
  • Anahtar Kelimeler: Raynaud's phenomenon, systemic lupus erythematosus, urotensin-II, ENDOTHELIAL DYSFUNCTION, PULMONARY-HYPERTENSION, DISEASE-ACTIVITY, RECEPTOR GPR14, PLASMA-LEVELS, NITRIC-OXIDE, ATHEROSCLEROSIS, LOCALIZATION, RESPONSES, HEALTH
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Aim: Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear.