Increased urotensin-II activity in patients with Raynaud's phenomenon and systemic lupus erythematosus

Buyukhatipoglu H., BUYUKASLAN H., Pehlivan Y., Ceylan N., Ulas T., Tarakcioglu M., ...More

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, vol.14, no.3, pp.276-281, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.1111/j.1756-185x.2011.01597.x
  • Journal Name: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.276-281
  • Keywords: Raynaud's phenomenon, systemic lupus erythematosus, urotensin-II, ENDOTHELIAL DYSFUNCTION, PULMONARY-HYPERTENSION, DISEASE-ACTIVITY, RECEPTOR GPR14, PLASMA-LEVELS, NITRIC-OXIDE, ATHEROSCLEROSIS, LOCALIZATION, RESPONSES, HEALTH
  • Akdeniz University Affiliated: No

Abstract

Aim: Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear.