THE VALUE OF CA-125, CA 19-9, INTERLEUKIN-6, INTERLEUKIN-8 AND HSCRP IN THE DIAGNOSIS OF ENDOMETRIOSIS

Sutcu H. K., Celik G. I. T., Akpak Y. K., Akar M., Taskin O., ÖZDEM S., ...More

ACTA MEDICA MEDITERRANEA, vol.31, no.4, pp.793-799, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2015
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.793-799
  • Keywords: Endometriosis, Serum Biomarkers, Non-Invasive Diagnosis, Laparoscopic Infertility Examination, PERITONEAL-FLUID, SERUM CA-125, WOMEN, MARKERS, PREDICTION, BIOMARKERS, CYTOKINES, CA125
  • Akdeniz University Affiliated: Yes

Abstract

Introduction: Endometriosis is a pelvic inflammatory process involving a malfunction in immune-related mechanisms. The pathogenesis of endometriosis is complex. However, this complex structure leads to the identification of disease with several potential diagnostic markers. The aim of our study was to develop a practical non-invasive test for the diagnosis of endometriosis by evaluating the serum levels of cancer antigen-125 (CA-125), cancer antigen 19-9 (CA 19-9), interleukin 6 (IL-6), interleukin 8 (IL-8) and high-sensitivity C-reactive protein (hsCRP) in patients with endometriosis.