The effect of pentoxifylline on haemolysis during cardiopulmonary bypass in open-heart surgery

Gölbaşı İ., Akbas H., Ozdem S., Ukan S., Ozdem S., Kabukcu H., ...Daha Fazla

ACTA CARDIOLOGICA, cilt.61, sa.1, ss.7-11, 2006 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.2143/ac.61.1.2005134
  • Dergi Adı: ACTA CARDIOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.7-11
  • Anahtar Kelimeler: pentoxifylline, haemolysis, cardiopulmonary bypass, haemoglobin, haptoglobin, INTERNAL THORACIC ARTERY, RED-CELL DEFORMABILITY, FREE HEMOGLOBIN, INFLAMMATORY RESPONSE, ISCHEMIA-REPERFUSION, LUNG, INHIBITION, ACTIVATION, INJURY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective - Haemolysis has long been recognized as one of the responses to cardiopulmonary bypass (CPB). Pentoxifylline (PTX), a methylxanthine derivative, has been known for many years for its haemorrheological properties. In this prospective, randomized study, we investigated whether a PTX treatment would reduce the haemolysis during CPB.