Differentiation between hepatic alveolar echinococcosis and primary hepatic malignancy with diffusion-weighted magnetic resonance imaging

SADE R., KANTARCI A., Ogul H., Gundogdu B., Aydinli B.

DIAGNOSTIC AND INTERVENTIONAL IMAGING, sa.3, ss.169-177, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.diii.2017.09.007
  • Dergi Adı: DIAGNOSTIC AND INTERVENTIONAL IMAGING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.169-177
  • Anahtar Kelimeler: Diffusion magnetic resonance imaging, Alveolar echinococcosis, Apparent diffusion coefficient (ADC), Hepatocellular carcinoma, Intrahepatic cholangiocarcinoma, FOCAL LIVER-LESIONS, HEPATOCELLULAR-CARCINOMA, MRI FINDINGS, CHOLANGIOCARCINOMA, DIAGNOSIS, BENIGN, MASSES
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: To determine the value of diffusion-weighted magnetic resonance imaging (DW-MRI) in discriminating between hepatic alveolar echinococcosis (AE) and hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Methods: We included 49 patients (27 men, 22 women; mean age: 52.02 +/- 9.76 [SD] years; range: 25-72 years) with 57 histopathologically confirmed hepatic AE lesions. Fifty patients (18 men, 32 women; mean age: 58.93 +/- 8.42 [SD] years; range: 42-71 years) with 61 histopathologically confirmed hepatocellular carcinoma and 50 patients (24 men, 26 women; mean age: 50.11 +/- 7.70 [SD] years; range: 38-69 years) with 54 histopathologically confirmed intrahepatic cholangiocarcinoma lesions were used as control groups. All patients had MRI examination of the liver that included conventional MRI sequences and DW-MRI using b values of 50, 400 and 800 s/mm2. Two radiologists evaluated conventional MRI and DW-MRI images and calculated ADC values of hepatic lesions. Results: The mean ADC value of solid components of hepatic AE lesions was 1.34 +/- 0.41 x 10-3 mm2/s (range: 0.9-1.59 x 10-3 mm2/s) and was significantly higher than that of the solid components of hepatocellular carcinoma lesions ( mean ADC value, 0.99 +/- 0.29 x 10-3 mm2/s; range: 0.7-1.15 x 10-3 mm2/s) and of intrahepatic cholangiocarcinoma lesions (mean ADC value, 1.05 +/- 0.22 x 10-3 mm2/s; range: 0.86-1.18 x 10-3 mm2/s) (P < 0.001). Conclusion: In general ADC values can help discriminate between AE and hepatocellular carcinoma and intrahepatic cholangiocarcinoma. However, the use of ADC values cannot help differentiating Type 4 AE from hepatocellular carcinoma or intrahepatic cholangiocarcinoma. (c) 2017 Editions francaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.