The relation of CD3, CD4, CD8 and PD-1 expression with tumor type and prognosis in epithelial ovarian cancers
GINEKOLOGIA POLSKA, vol.92, no.5, pp.344-351, 2021 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 92 Issue: 5
- Publication Date: 2021
- Doi Number: 10.5603/gp.a2021.0080
- Journal Name: GINEKOLOGIA POLSKA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, Gender Studies Database, MEDLINE, Directory of Open Access Journals
- Page Numbers: pp.344-351
- Keywords: ovarian cancer, PD-1, CD3, CD4, stromal lymphocytes, INFILTRATING LYMPHOCYTES, T-CELLS, FAVORABLE PROGNOSIS, BLOCKADE
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: Yes
Abstract
Objectives: Ovarian cancer is a heterogeneous disease, where chronic inflammation plays a key role in carcinogenesis. In this study, it is aimed to analyze the relationship with prognosis and chemotherapy response to clinicopathological variables in epithelial ovarian cancers such as proliferation of PD-1 +, CD8 +, CD4 +, CD3 + T-lymphocytes infiltrating the tumor and tumor stroma.