The relation of CD3, CD4, CD8 and PD-1 expression with tumor type and prognosis in epithelial ovarian cancers

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Karakaya Y. A., Atigan A., Guler O. T., Demiray A. G., BİR F.

GINEKOLOGIA POLSKA, cilt.92, sa.5, ss.344-351, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 92 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5603/gp.a2021.0080
  • Dergi Adı: GINEKOLOGIA POLSKA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, Gender Studies Database, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.344-351
  • Anahtar Kelimeler: ovarian cancer, PD-1, CD3, CD4, stromal lymphocytes, INFILTRATING LYMPHOCYTES, T-CELLS, FAVORABLE PROGNOSIS, BLOCKADE
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objectives: Ovarian cancer is a heterogeneous disease, where chronic inflammation plays a key role in carcinogenesis. In this study, it is aimed to analyze the relationship with prognosis and chemotherapy response to clinicopathological variables in epithelial ovarian cancers such as proliferation of PD-1 +, CD8 +, CD4 +, CD3 + T-lymphocytes infiltrating the tumor and tumor stroma.