The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury


ÇAKIR T., POLAT C., Basturk A., GÜL M., ASLANER A., DURGUT H., ...More

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.19, no.11, pp.2132-2139, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 11
  • Publication Date: 2015
  • Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2132-2139
  • Keywords: Alpha lipoic acid, Methotrexate, Kidney, Oxidative injury, HIGH-DOSE METHOTREXATE, TOXICITY, STRESS, MYELOPEROXIDASE, MELATONIN, RELEASE
  • Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: The purpose of this study is to determine the antioxidant and anti-inflammatory effects of alpha lipoic acid (ALA) on methotrexate (MTX) induced kidney injury in rats.