The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury

ÇAKIR, TUĞÇE; POLAT, C.; Basturk, AHMET; GÜL, MEHMET; ASLANER, A.; DURGUT, H.; SEHIRLI, A.; AYKAC, A.; Bahar, L.; SABUNCUOĞLU, Mehmet

The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury

Copy For Citation

ÇAKIR T., POLAT C., Basturk A., GÜL M., ASLANER A., DURGUT H., ...More

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.19, no.11, pp.2132-2139, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 19 Issue: 11
Publication Date: 2015
Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.2132-2139
Keywords: Alpha lipoic acid, Methotrexate, Kidney, Oxidative injury, HIGH-DOSE METHOTREXATE, TOXICITY, STRESS, MYELOPEROXIDASE, MELATONIN, RELEASE
Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: The purpose of this study is to determine the antioxidant and anti-inflammatory effects of alpha lipoic acid (ALA) on methotrexate (MTX) induced kidney injury in rats.