The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury

ÇAKIR, TUĞÇE; POLAT, MEHMET; Basturk, AHMET; GÜL, MEHMET; ASLANER, A.; DURGUT, H.; SEHIRLI, A.; AYKAC, A.; Bahar, L.; SABUNCUOĞLU, Mehmet

The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury

ÇAKIR T., POLAT C., Basturk A., GÜL M., ASLANER A., DURGUT H., ...Daha Fazla

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.19, sa.11, ss.2132-2139, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19 Sayı: 11
Basım Tarihi: 2015
Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2132-2139
Anahtar Kelimeler: Alpha lipoic acid, Methotrexate, Kidney, Oxidative injury, HIGH-DOSE METHOTREXATE, TOXICITY, STRESS, MYELOPEROXIDASE, MELATONIN, RELEASE
Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: The purpose of this study is to determine the antioxidant and anti-inflammatory effects of alpha lipoic acid (ALA) on methotrexate (MTX) induced kidney injury in rats.