Akademik Veri Yönetim Sistemi
JOURNAL OF STOMATOLOGY, ORAL AND MAXILLOFACIAL SURGERY, ss.1-17, 2024 (SCI-Expanded)
Aim: Oral malignant melanoma (OMM) is a rare and aggressive malignant tumour arising
from the proliferation of melanocytes and accounts for only 0.5% of all oral malignancies. It
is invasive and tends to metastasise. The aim of this study is to determine the patient profile of
OMM and to provide information about the clinical features and treatment plans of the
disease.
Materials and Methods: The Pubmed database was searched for OMM cases published as
case reports in the last 10 years. The search was limited to English and open-access case
reports. A total of 49 OMMs in 45 patients from 43 case reports were analyzed. In addition to
the age, gender, smoking and alcohol consumption habits of the patients, data on the signs and
symptoms of OMM, location of the lesion, imaging modalities used in diagnosis and
treatment, lymph node involvement, presence of metastasis, survival time, and treatment
modalities were recorded.
Results: In OMM cases, 18 (40%) of the patients were female, 27 (60%) were male, and the
mean age was 53.13 ± 16.09 years. The most common symptom was "swelling" (n= 23,
33.8%) and the most common finding was "hyperpigmentation" (n= 40, 24.4%). The most
common site of OMM was the maxilla (n= 21, 46.7%). According to the rate of use of
imaging modalities in the cases, it was determined that "advanced imaging modalities" were
mostly used (n=24, 53.3%). It was determined that 22.2% (n=10) of the patients died within
the first 5 years. Combined treatment (n= 21, 46.5%) were mostly applied to the patients.
Conclusion: OMM is more common in the maxilla, in males and in the fifth decade of life,
and advanced imaging modalities are most commonly used to detect the disease. Because of
its poor prognosis, knowing the patient profile and common clinical features of OMM will
increase the clinical awareness of physicians.