The Evaluation of the Performance of C. Diff Quik Chek Complete and Toxin A plus B (Clostridium difficile) DUO Diagnostic Tests Compared with Toxigenic Culture in the Diagnosis of Clostridium difficile Infection

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Yazısız H., Ozyurt Ö., Öngüt G., Baysan B. O., Dönmez L., Gunseren F., ...More

CLINICAL LABORATORY, vol.66, no.4, pp.537-540, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.7754/clin.lab.2019.190713
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.537-540
  • Keywords: Clostridium difficile infection, Clostridium difficile toxin A, Clostridium difficile toxin B, glutamate dehydrogenase, toxigenic culture, GLUTAMATE-DEHYDROGENASE, ENZYME-IMMUNOASSAY, ASSAYS
  • Akdeniz University Affiliated: Yes

Abstract

Background: Clostridium difficile is an important cause of nosocomial diarrhea and the best standard laboratory method for the diagnosis of C. difficile infection is controversial. In this study, we aimed to investigate the performance of Toxin A + B (Clostridium difficile) DUO kit which detects C difficile toxin A and B by the immunochromatographic method and C. Diff Quik Chek Complete (QCC) rapid membrane immunoassay kit which determines the presence of glutamate dehydrogenase (GDH) and C. difficile toxin A and B in stool samples, compared with toxigenic culture in the diagnosis of C. difficile infection.