Research Information System
3rd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2020)., Ankara, Turkey, 19 - 20 March 2020, pp.105, (Full Text)
It is known that components such as polyphenols, flavonoids and polysaccharides have antioxidant and antimicrobial
activity in macroalgae in aquatic environments. In this study, it was aimed to determine the antimicrobial activities of
Enteromorpha intestinalis methanol, 70% ethanol and water extracts against different pathogenic microorganisms, which are
economically important marine macroalgae. According to Broth Microdilution Method; Antimicrobial activities of different
extracts of the studied species against Escherichia coli (ATTC 25922), Pseudomonas aeruginosa (ATTC 27853), Klebsiella
pneumoniae (ATTC 70603), Staphylococcus aureus (ATTC 43300), Salmonella enteritidis (ATTC 13076), Sarcina lutea
(ATTC 9341) and Bacillus cereus (ATTC 11778) standard bacterial strains and Candida albicans fungus strain were
evaluated by determining the Minimum Inhibition Concentration (MIC).According to the findings, it was observed that the
water extract of the studied species showed no antimicrobial activity against any test organism. The methanol extract of
Enteromorpha intestinalis was found to have antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus
aureus, Sarcina lutea ,Bacillus cereus and Candida albicans strain, while ethanol extract was observed against
Pseudomonas aeruginosa ,Sarcina lutea and Candida albicans strains. The highest antibacterial effect was observed in
Entereomorpha intestinalis methanol extract and the most effective strain was Bacillus cereus (0.390 mg / ml). Nowadays,
the rise of resistant bacteria and pathogens that arise against conventional chemotherapeutic compounds renders the use of
these compounds useless. In this case, algae are of great importance in terms of being very useful drug raw material,
containing the basic components, being more effective and less toxic, as well as being models for drugs with original druglike
physiological activity. Since the data obtained with this study are intended for prospective application, it is thought that
alternative drug applications will be provided as a basis for the studies aimed at reducing the use of commonly used
antibiotic and antifungal agents against pathogenic microorganisms.