Determination of antimicrobial activity of different extracts of Enteromorpha intestinalis (Linnaeus) Nees 1820 against pathogenic microorganism.


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OKUDAN E. Ş.

3rd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2020)., Ankara, Turkey, 19 - 20 March 2020, pp.105, (Full Text)

  • Publication Type: Conference Paper / Full Text
  • City: Ankara
  • Country: Turkey
  • Page Numbers: pp.105
  • Akdeniz University Affiliated: Yes

Abstract

It is known that components such as polyphenols, flavonoids and polysaccharides have antioxidant and antimicrobial

activity in macroalgae in aquatic environments. In this study, it was aimed to determine the antimicrobial activities of

Enteromorpha intestinalis methanol, 70% ethanol and water extracts against different pathogenic microorganisms, which are

economically important marine macroalgae. According to Broth Microdilution Method; Antimicrobial activities of different

extracts of the studied species against Escherichia coli (ATTC 25922), Pseudomonas aeruginosa (ATTC 27853), Klebsiella

pneumoniae (ATTC 70603), Staphylococcus aureus (ATTC 43300), Salmonella enteritidis (ATTC 13076), Sarcina lutea

(ATTC 9341) and Bacillus cereus (ATTC 11778) standard bacterial strains and Candida albicans fungus strain were

evaluated by determining the Minimum Inhibition Concentration (MIC).According to the findings, it was observed that the

water extract of the studied species showed no antimicrobial activity against any test organism. The methanol extract of

Enteromorpha intestinalis was found to have antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus

aureus, Sarcina lutea ,Bacillus cereus and Candida albicans strain, while ethanol extract was observed against

Pseudomonas aeruginosa ,Sarcina lutea and Candida albicans strains. The highest antibacterial effect was observed in

Entereomorpha intestinalis methanol extract and the most effective strain was Bacillus cereus (0.390 mg / ml). Nowadays,

the rise of resistant bacteria and pathogens that arise against conventional chemotherapeutic compounds renders the use of

these compounds useless. In this case, algae are of great importance in terms of being very useful drug raw material,

containing the basic components, being more effective and less toxic, as well as being models for drugs with original druglike

physiological activity. Since the data obtained with this study are intended for prospective application, it is thought that

alternative drug applications will be provided as a basis for the studies aimed at reducing the use of commonly used

antibiotic and antifungal agents against pathogenic microorganisms.