Neoangiogenesis and expression of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor, and glucose transporter-1 in endometrioid type endometrium adenocarcinomas

ÖZBUDAK, İREM; KARAVELI, Seyda; SIMSEK, Tayyup; ERDOĞAN, GÜLGÜN; PESTERELI, Elif

doi:10.1016/j.ygyno.2007.11.028

Neoangiogenesis and expression of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor, and glucose transporter-1 in endometrioid type endometrium adenocarcinomas

ÖZBUDAK İ. H., KARAVELI S., SIMSEK T., ERDOĞAN G., PESTERELI E.

GYNECOLOGIC ONCOLOGY, cilt.108, sa.3, ss.603-608, 2008 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 108 Sayı: 3
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.ygyno.2007.11.028
Dergi Adı: GYNECOLOGIC ONCOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.603-608
Anahtar Kelimeler: HIF-1 alpha, VEGF, GLUT-1, neoangiogenesis, endometrium adenocarcinoma, TUMOR ANGIOGENESIS, FACTOR 1-ALPHA, CARCINOMA, METASTASIS, PROGNOSIS, 2-ALPHA, BIOLOGY, CANCER, GLUT-1
Akdeniz Üniversitesi Adresli: Evet

Özet

Objective. Hypoxia Inducible Factor-lot (HIF-1 alpha) is a transcriptional factor that activates multiple genes including Vascular Endothelial Growth Factor (VEGF) and glucose transporter-1 (GLUT-1) in response to hypoxia and promotes neoangiogenesis.