Evaluation of mTOR signaling pathway proteins in rat gastric mucosa exposed to sulfite and ghrelin

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ERCAN S., Sahin P., Kencebay C., DERİN N., OZENCI C. C.

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.29, sa.1, ss.94-100, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/tjg.2017.17294
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.94-100
  • Anahtar Kelimeler: mTOR proteins, sodium metabisulfite, ghrelin, gastric mucosa, TUBEROUS SCLEROSIS COMPLEX, VISUAL-EVOKED POTENTIALS, SODIUM METABISULFITE, ADULT MICE, APOPTOSIS, PROLIFERATION, MECHANISM, PEPTIDE, STRESS, KINASE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background/Aims: Mammalian target of rapamycin (mTOR) signaling serves as a central regulator of cell growth, proliferation, and survival. In this study, we planned to evaluate the expressions of mTOR signaling constituents (p-p70S6K, p-mTOR, and p-Tuberin) in rat gastric mucosa and to compare the results in sulfite-and sulfite+ ghrelin-exposed groups.