Approach to malign melanoma in anorectal area Anorektal bölgedeki malign melanomlara yaklaşım


PÜLAT H., KARAKÖSE O., SABUNCUOĞLU M. Z., BENZİN M. F., ÇETİN R., ZİHNİ İ.

Journal of Clinical and Analytical Medicine, vol.7, pp.209-212, 2016 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 7
  • Publication Date: 2016
  • Doi Number: 10.4328/jcam.3245
  • Journal Name: Journal of Clinical and Analytical Medicine
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.209-212
  • Keywords: Anal Canal, Malign Melanoma, Rectum, Surgery
  • Akdeniz University Affiliated: No

Abstract

Aim: Anorectal malign melanoma comprise 0.2-1% of all malign melanoma. They are extremely aggressive. Most patients are lost beacuse of incurable systemic illness. In our study, we aim to evaluate the results of surgical and oncological follow-up of our patients that we operated because of anorectal malign melanoma. Material and Method: Our 4 patients operated because of anorectal malign melanoma between October 2008 and April 2013 were analysed. The patients were analysed in terms of demographic datas, com-plaint and its time, physical examination and imaging findings, treatment procedure, local recurrence or presence of metastasis and follow-up results. Results: Our study group comprised 4 people (2 men and 2 women) with the mean age of 64,2 years. The main complaint was rectal bleeding. The avarage complaint duration was 7.5 months. In all patients, anorectal mass was detected after physical examination and imaging studies. Biopsies of the mass were reported to be consistent with malign melanoma. With the further studies, one patient was detected to have metastasis in liver. Abdominoperineal resection was applied to one patient after wide local excision and to three patients during the first aplication. The avarage follow-up time was 19,25 months. The avarage diameter of tumor was 3,9 cm. One patient was applied lymph node dissection because of recurrence in iliac region. The avarage stay time at hospital of the patients who had no postoperative problems was 9,7 days. During follow-up time, three of the patients died because of common metastasis. A patient followed regularly is still continuing his life without illness in his postoperative 22nd month. Discussion: Anorectal malign melanoma is a rare, with a bad prognosis and a late diagnosed entity as it has a similarity with benign illnesses which are mostly seen in anorectal area in terms of clinical symptoma. To correct the prognosis of the illness, the suitable surgery and adjuvant treatment must be planned after early diagnosis as soon as possible.