Mannitol Attenuates Acute Lung Injury Induced by Infrarenal Aortic Occlusion-Reperfusion in Rats

Teke, Zafer; Adali, Fahri; Kelten, E.; ENLİ, YAŞAR; Sackan, K.; Karaman, Kerem; Akbulut, Metin; Goksin, Ibrahim

doi:10.1007/s00595-010-4394-x

Mannitol Attenuates Acute Lung Injury Induced by Infrarenal Aortic Occlusion-Reperfusion in Rats

Teke Z., Adali F., Kelten E. C., ENLİ Y., Sackan K. G., Karaman K., ...Daha Fazla

SURGERY TODAY, cilt.41, sa.7, ss.955-965, 2011 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 41 Sayı: 7
Basım Tarihi: 2011
Doi Numarası: 10.1007/s00595-010-4394-x
Dergi Adı: SURGERY TODAY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.955-965
Anahtar Kelimeler: Ischemia/reperfusion, Aortic occlusion, Acute lung injury, Pulmonary microvascular dysfunction, Neutrophil, Myeloperoxidase, Malondialdehyde, Glutathione, Superoxide dismutase, INTESTINAL ISCHEMIA-REPERFUSION, TUMOR-NECROSIS-FACTOR, SKELETAL-MUSCLE, HYPERTONIC MANNITOL, NITRIC-OXIDE, MODEL, ISCHEMIA/REPERFUSION, PREVENTION, REDUCTION, RABBIT
Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose. Mannitol is used as a treatment for ischemia/reperfusion (IR) injury of various organs in humans, despite the fact that its effectiveness in vivo is still disputed. The purpose of this study was to determine the effects of mannitol on acute lung injury (ALI) induced by infrarenal aortic occlusion.