Mannitol Attenuates Acute Lung Injury Induced by Infrarenal Aortic Occlusion-Reperfusion in Rats

Teke Z., Adali F., Kelten E. C., ENLİ Y., Sackan K. G., Karaman K., ...More

SURGERY TODAY, vol.41, no.7, pp.955-965, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 7
  • Publication Date: 2011
  • Doi Number: 10.1007/s00595-010-4394-x
  • Journal Name: SURGERY TODAY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.955-965
  • Keywords: Ischemia/reperfusion, Aortic occlusion, Acute lung injury, Pulmonary microvascular dysfunction, Neutrophil, Myeloperoxidase, Malondialdehyde, Glutathione, Superoxide dismutase, INTESTINAL ISCHEMIA-REPERFUSION, TUMOR-NECROSIS-FACTOR, SKELETAL-MUSCLE, HYPERTONIC MANNITOL, NITRIC-OXIDE, MODEL, ISCHEMIA/REPERFUSION, PREVENTION, REDUCTION, RABBIT
  • Akdeniz University Affiliated: Yes

Abstract

Purpose. Mannitol is used as a treatment for ischemia/reperfusion (IR) injury of various organs in humans, despite the fact that its effectiveness in vivo is still disputed. The purpose of this study was to determine the effects of mannitol on acute lung injury (ALI) induced by infrarenal aortic occlusion.