Triploidy in a growth discordant twin pregnancy after intracytoplasmic sperm injection treatment - Case report

Mendilcioglu I., OZCAN M., BAGCI G., Simsek M., KURSUN S., LULECI G., ...More

FETAL DIAGNOSIS AND THERAPY, vol.21, no.1, pp.65-67, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1159/000089050
  • Journal Name: FETAL DIAGNOSIS AND THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.65-67
  • Keywords: intracytoplasmic sperm injection, selective feticide, triploidy, growth discordant twin, FETUSES, ICSI, ANOMALIES, ORIGIN
  • Akdeniz University Affiliated: Yes

Abstract

Objective: We report on a case of a triploidy in one fetus of a twin pregnancy who presented with the findings of growth discordance. Methods: Three weeks' difference between fetuses in ultrasonographic measurements in the first trimester was observed in a twin pregnancy following intracytoplasmic sperm injection ( ICSI) treatment for male infertility. Hydrocephaly developed in the growth-discordant fetus subsequently. Amniocentesis for both fetuses and selective feticide for the abnormal one was performed at 19 weeks' gestation through a single insertion. Fetal karyotype of the abnormal one was 69,XXX and the healthy one was 46,XX. Conclusion: Early developed growth discordance in a twin pregnancy may be a sign of chromosomal abnormality such as triploidy. Those cases should be karyotyped without delay to decrease preterm delivery risk of possible selective feticide. Copyright (c) 2006 S. Karger AG, Basel.