Triploidy in a growth discordant twin pregnancy after intracytoplasmic sperm injection treatment - Case report

Mendilcioglu I., OZCAN M., BAGCI G., Simsek M., KURSUN S., LULECI G., ...Daha Fazla

FETAL DIAGNOSIS AND THERAPY, cilt.21, sa.1, ss.65-67, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1159/000089050
  • Dergi Adı: FETAL DIAGNOSIS AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.65-67
  • Anahtar Kelimeler: intracytoplasmic sperm injection, selective feticide, triploidy, growth discordant twin, FETUSES, ICSI, ANOMALIES, ORIGIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: We report on a case of a triploidy in one fetus of a twin pregnancy who presented with the findings of growth discordance. Methods: Three weeks' difference between fetuses in ultrasonographic measurements in the first trimester was observed in a twin pregnancy following intracytoplasmic sperm injection ( ICSI) treatment for male infertility. Hydrocephaly developed in the growth-discordant fetus subsequently. Amniocentesis for both fetuses and selective feticide for the abnormal one was performed at 19 weeks' gestation through a single insertion. Fetal karyotype of the abnormal one was 69,XXX and the healthy one was 46,XX. Conclusion: Early developed growth discordance in a twin pregnancy may be a sign of chromosomal abnormality such as triploidy. Those cases should be karyotyped without delay to decrease preterm delivery risk of possible selective feticide. Copyright (c) 2006 S. Karger AG, Basel.