Triploidy in a growth discordant twin pregnancy after intracytoplasmic sperm injection treatment - Case report
FETAL DIAGNOSIS AND THERAPY, cilt.21, sa.1, ss.65-67, 2006 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 1
- Basım Tarihi: 2006
- Doi Numarası: 10.1159/000089050
- Dergi Adı: FETAL DIAGNOSIS AND THERAPY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.65-67
- Anahtar Kelimeler: intracytoplasmic sperm injection, selective feticide, triploidy, growth discordant twin, FETUSES, ICSI, ANOMALIES, ORIGIN
- Akdeniz Üniversitesi Adresli: Evet
Özet
Objective: We report on a case of a triploidy in one fetus of a twin pregnancy who presented with the findings of growth discordance. Methods: Three weeks' difference between fetuses in ultrasonographic measurements in the first trimester was observed in a twin pregnancy following intracytoplasmic sperm injection ( ICSI) treatment for male infertility. Hydrocephaly developed in the growth-discordant fetus subsequently. Amniocentesis for both fetuses and selective feticide for the abnormal one was performed at 19 weeks' gestation through a single insertion. Fetal karyotype of the abnormal one was 69,XXX and the healthy one was 46,XX. Conclusion: Early developed growth discordance in a twin pregnancy may be a sign of chromosomal abnormality such as triploidy. Those cases should be karyotyped without delay to decrease preterm delivery risk of possible selective feticide. Copyright (c) 2006 S. Karger AG, Basel.