A RARE ENTITY OF ACQUIRED IDIOPATHIC GENERALISED ANHIDROSIS WHICH HAS BEEN SUCCESSFULLY TREATED WITH PULSE STEROID THERAPY: DOES THE HISTOPATHOLOGY PREDICT THE TREATMENT RESPONSE?

Oktem E. O., Cankaya S., Uykur A. B., ŞİMŞEK ERDEM N., Yulug B.

IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE, cilt.73, sa.9-10, ss.349-353, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 73 Sayı: 9-10
  • Basım Tarihi: 2020
  • Doi Numarası: 10.18071/isz.73.0349
  • Dergi Adı: IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.349-353
  • Anahtar Kelimeler: acquired idiopathic generalized anhidrosis, AIGA, anhidrosis, corticosteroid therapy, CHOLINERGIC URTICARIA, HYPOHIDROSIS, MECHANISMS, DIAGNOSIS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Acquired idiopathic generalised anhidrosis is an uncommon sweating disorder characterized by loss of sweating in the absence of any neurologic, metabolic or sweat gland abnormalities. Although some possible immunological and structural mechanisms have been proposed for this rare entity, the definitive pathophysiology is still unclear. Despite some successfully treated cases with systemic corticosteroid application, the dose and route of steroid application are controversial. Here, we present a 41-year-old man with lack of generalised sweating who has been successfully treated with high dose pulse intravenous prednisolone. We have discussed his clinical and histopathological findings as well as the treatment options in view of the current literature.