Akademik Veri Yönetim Sistemi
Heroin Addiction and Related Clinical Problems, cilt.26, sa.1, 2024 (SSCI)
Aim. We aimed to compare opiate use disorder patients (OUD) in remission with healthy volunteers in terms of nighteating syndrome, sleep disorder, and impulsivity and to determine the relationship between these variables and craving. Methods. Using a cross-sectional design, we compared 100 OUD patients who had been in remission for at least one month on buprenorphine/naloxone therapy and were not using any other medication and 100 healthy volunteers. Sociodemographic Form, the Structured Clinical Interview for DSM-5, the Pittsburgh Sleep Quality Index (PSQI), the Nighteating Questionnaire (NEQ), and the Barratt Impulsivity Scale-11 (BIS-11) were administered to all participants. Craving was assessed in the OUD group with the Substance Craving Scale (SCS). Results. The NEQ total score (p<0.001), BIS-11 total score (p=0.009), and PSQI score (p<0.001) were higher in the OUD group compared to healthy controls. 26% of the OUD group had night-eating syndrome based on the cutoff score of the NEQ, and 67% had poor sleep quality, according to the PSQI cutoff score. A regression analysis showed that poor sleep quality (β=0.200, p=0.039) and increased impulsivity scores (β=0.345, p<0.001) were positively and independently associated with substance craving scores. Conclusions. Our results suggest that OUD patients in remission have worse sleep quality, a higher incidence of night-eating syndromes, and higher impulsivity compared with healthy controls. Additionally, our findings showed poor sleep quality and impulsivity directly predicted craving in OUD.